Lion’s Mane – Organic Hericium

Lion's Mane Organic Hericium
Full-spectrum Hericium. Fruiting body and mycelium, standardised — not grain filler.
- Sharper recall under heavy cognitive load
- Steadier focus through long deep-work blocks
- Genuine NGF support — the neuroplasticity mechanism
- Full-spectrum, not grain filler — fruiting body + mycelium
1000 mg full-spectrum Hericium erinaceus — fruiting body and mycelium, standardised to 40% polysaccharides. Both NGF-active compound families, in one capsule.
Most Lion's Mane is mycelium grown on grain — 70% starch, almost no active compounds. This is real fruiting body plus mycelium, standardised to 40% polysaccharides.
Hericenones drive NGF synthesis in the hippocampus — the mechanism behind Mori's 16-week RCT showing improved cognition vs placebo.
Erinacines from the mycelium cross the blood-brain barrier — a central pathway the fruiting body alone can't reach.
Pilot RCT data shows lower stress and steadier mood alongside the cognitive gains — a benefit that compounds over weeks.
Three peer-reviewed signals — clinical doses, human trials, real outcomes.
Every active, every dose — disclosed in full. No proprietary blend, nothing under-dosed.
Two NGF pathways. One immune layer.
Hericenones from the fruiting body upregulate NGF in hippocampal neurons — the basis of synaptic plasticity and neuron survival.
Erinacines from the mycelium cross the blood-brain barrier to raise NGF directly in the brain — the pathway fruiting-body-only products miss.
40% beta-glucans modulate neuroinflammatory signalling — clearing the low-grade inflammation that quietly drags on cognition.
Subtle baseline shift — clearer mornings, less cognitive fatigue. NGF signalling is establishing.
Word retrieval and working memory under load improve. The most-reported window for noticeable focus gains.
The Mori RCT window — cognitive scores diverge from placebo. Mood and stress steady too.
Structural maintenance. NGF support holds for as long as you keep taking it. A long-game compound.
Compound-based expectation — not medical advice. Individual response varies.
Two capsules in the morning with water. Effect is cumulative — give it the full 8–16 weeks the clinical trials used. Consistency beats intensity.
Peer-reviewed. Human trials.
16-week DB-RCT in 30 older adults with mild cognitive impairment: 3g/day significantly improved cognitive function scale scores vs placebo at weeks 8, 12, and 16. Improvement reversed 4 weeks after cessation — indicating an active mechanism, not placebo durability.
Mori K et al. Phytother Res. 2009;23(3):367–72 ↗Double-blind parallel-groups pilot in healthy young adults: 28-day supplementation improved cognitive function, reduced perceived stress, and improved mood scores vs placebo — extending the evidence base beyond older-adult populations.
Docherty S et al. Nutrients. 2023;15(22):4842 ↗DB-RCT in healthy younger adults: acute single-dose of standardised extract improved attention, cognitive processing speed, and mood vs placebo in a rigorously controlled crossover design — demonstrating both acute and cumulative cognitive effects.
Surendran G et al. Front Nutr. 2025;12:1405796 ↗Oral supplementation with erinacine A-enriched mycelium demonstrated significant NGF induction in brain tissue and improved hippocampal neurogenesis; erinacines confirmed to cross the blood-brain barrier with direct CNS NGF upregulation.
Li IC et al. Behav Neurol. 2018;2018:5802634 ↗checked the literature first — mori et al is the real clinical study, 16 weeks, significant vs placebo. week 8 and recall under load is noticeably different. not a stimulant, a baseline shift.
two other brands before this were mycelium on brown rice — lab tests showed 70%+ starch. this is fruiting body + mycelium at 40% polysaccharides, a number you can verify. 10 weeks in, clarity on long sessions is real.
first month i felt nothing and almost quit. kept going because the trials say 4–8 weeks minimum. week 8 the afternoon fog lifted. if you stop at week 4 you're doing it wrong. knocking a star for the slow start.
running this with the nad+ from substrat — lion's mane for plasticity, nad+ for energy. genuinely no overlap. week 10 and morning clarity is the best it's been in a while.
formula and sourcing are legit. only gripe: 30 servings means reordering monthly, and you need 3+ months for the full effect. if a 90-day format existed i'd buy it. still ordering.
everyone fixates on 1000mg. the real signal is both fruiting body and mycelium — erinacines need one, hericenones the other. one without the other halves the mechanism. this has both at 40%.